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Natalizumab

ResearchSpeak & #ThinkHand: ECTRIMS highlight sustained improvement in SPMS Wow who would have thought you would get improved function in advanced SPMS? #ThinkHand #ECTRIMS2016 #ResearchSpeak #MSBlog "The poster below is one of my ECTRIMS highlights. It has made me think differently about MS in particular about the mechanisms behind the improvement in neurological function. In short if the natalizumab in SPMS trial (ASCEND study) had been designed with the primary outcome being sustained…

A five-year study comparing the efficacy of different treatments for relapsing-remitting multiple sclerosis (RRMS) found that, in general, Lemtrada (alemtuzumab) and Tysabri (natalizumab) are more …

von Multiple Sclerosis News Today

Short Transition Period Between Natalizumab, Fingolimod RRMS Therapies Suggested

Biogen Idec's Study Reviews Positive Results Over Five Years of Tecfidera RRMS Treatment

von Multiple Sclerosis News Today

Natalizumab (Tysabri) Targets Molecule Crucial for Type of B-Cell to Accumulate in the Brain

Natalizumab (Tysabri) Targets Molecule Crucial for Type of B-Cell to Accumulate in the Brain - Multiple Sclerosis News Today

von Multiple Sclerosis News Today

Natalizumab (Tysabri) Targets Molecule Crucial for Type of B-Cell to Accumulate in the Brain

Read about the report that the natalizumab target - VLA4 - is involved in the accumulation of Bregs in the brain of mice with EAE.

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The multiple sclerosis drug Tysabri (natalizumab) increases the risk of a fatal brain virus ten-fold. Progressive multifocal leukoencephalopathy (PML) is a rare disease that attacks the brain’s white matter—but it becomes more common when the immune system is compromised, as can happen when people take immunosuppressive drugs, say researchers.

von Multiple Sclerosis News Today

Tysabri Protects Against Relapse in Multiple Sclerosis, According To Study

Tysabri Protects Against Relapse in Multiple Sclerosis, patients are a a high risk for developing PML. Many multiple sclerosis patients are also treated with natalizumab, which is an monoclonal antibody immunosuppressive medication. Putting the two together, some multiple sclerosis patients see a risk for extended use of Tysabri and desire a different treatment. “It’s difficult for patients to make decisions, In his experience, when the risk of PML for multiple scleros